Ewan McGregor as Valiant (voice); Ricky Gervais as Bugsy (voice); Tim Curry as Von Talon (voice); Jim Broadbent as Sergeant (voice); Hugh Laurie as Gutsy (voice); John Cleese as Mercury (voice); John Hurt as Felix (voice); Pip Torrens as Lofty (voice); Rik Mayall as Cufflingk (voice); Olivia Williams as Victoria (voice)

Nicolas Cage as Randy; Deborah Foreman as Julie Richman; Elizabeth Daily as Loryn; Michael Bowen as Tommy; Cameron Dye as Fred Bailey; Heidi Holicker as Stacey; Michelle Meyrink as Suzi Brent; Tina Theberge as Samantha; Lee Purcell as Beth Brent; Richard Sanders as Drivers' Ed Teacher

Nicolas Cage as Peter Loew; Maria Conchita Alonso as Alva Restrepo; Jennifer Beals as Rachel; Elizabeth Ashley as Dr. Glaser; Kasi Lemmons as Jackie; Bob Lujan as Emilio; Jessica Lundy as Sharon; Johnny Walker as Donald; Boris Leskin as Fantasy Cabbie; Michael Knowles as Andrew

Denzel Washington as Lt. Parker Barnes; Kelly Lynch as Dr. Madison Carter; Russell Crowe as SID 6.7; Stephen Spinella as Dr. Darrel Lindenmeyer; William Forsythe as William Cochran; Louise Fletcher as Commissioner Elizabeth Deane; William Fichtner as Wallace; Costas Mandylor as John Donovan; Kevin J. O'Connor as Clyde Reilly; Kaley Cuoco as Karin

Radha Mitchell as Georgia Perry; Susannah York as Carolyn Perry; Ray Barrett as Bill Perry; Dominic Purcell as Luke (as Domenic Purcell); Tottie Goldsmith as Casey; Che Timmins as Kai; Christopher Kirby as Rob (as Chris Kirby); Jan Friedl as Bev (as Jan Freidl); Soula Alexander; Roberta Connelly as Barbie