Bill Bellamy as DEA Agent Marcus Hill (voice); Michael Madsen as Detective Jack Frozenski (voice); Ron Perlman as Captain Joe Kowalski (voice); Michael Wincott as Mr. Big (voice); Vanessa Marshall as Daniels/Enforcer/Hooker (voice); Brigitte Burdine as Civilian (voice); Henry Dittman as Buyer/American Jumper/Civilian/Thug/Cop (voice); Andrι Sogliuzzo as Jose the Hook/Cop/Thug (voice) (as Andre Sogliuzzo); Andrea M. Metty as Civilian (voice) (as Andrea Metty); Michael Bell as Supplier/Thug/Cop/Jumper#2/Bum (voice); Jason Patric; Chi McBride; Ray Liotta

Nicolas Cage as Ben Gates; Diane Kruger as Abigail Chase; Justin Bartha as Riley Poole; Sean Bean as Ian Howe; Jon Voight as Patrick Gates; Harvey Keitel as Sadusky; Christopher Plummer as John Adams Gates; David Dayan Fisher as Shaw; Stewart Finlay-McLennan as Powell; Oleg Taktarov as Shippen

Nicolas Cage as Ben Gates

Nicolas Cage as Cris Johnson; Julianne Moore as Callie Ferris

Russell Crowe as FBI Agent Zack Grant; Helen Slater as Mary; Etsushi Toyokawa as Yuji Kobayashi, Yakuza Assassin; Michael Lerner as Frank Serlano; Kyusaku Shimada as Tetsuro; Kristopher Logan as Mr. Contingency, Serlano Henchman; Kelly Hu as Seiko Kobayashi; Andrew J. Ferchland as Eric Grant; Ian Ziering as Victor Serlano; Monty Bane as Goatee

Paul Newman as Sully Sullivan; Jessica Tandy as Miss Beryl Peoples; Bruce Willis as Carl Roebuck; Melanie Griffith as Toby Roebuck; Dylan Walsh as Peter Sullivan; Pruitt Taylor Vince as Rub Squeers; Gene Saks as Wirf Wirfley; Josef Sommer as Clive Peoples, Jr.; Philip Seymour Hoffman as Officer Raymer; Philip Bosco as Judge Flatt

Elijah Wood as North; Jason Alexander as North's Dad; Julia Louis-Dreyfus as North's Mom; Marc Shaiman as Piano Player; Jussie Smollett as Adam; Taylor Fry as Zoe; Alana Austin as Sarah; Peg Shirley as Teacher; Chuck Cooper as Umpire; Alan Zweibel as Coach